ASTER LABORATORY

Notch Mediated Processes in
Development & Disease

Notch signaling plays a crucial role in cellular development and many disease pathologies

  • We study how Notch signaling contributes to the pathogenesis of solid & hematopoietic malignancies
  • We aim to determine how Notch regulates gene expression in a cell-lineage-specific fashion, we an eye towards developing effective Notch-directed therapeutic strategies
  • We do our Notch work within a unique longstanding highly interactive collaboration with the labs of Stephen Blacklow (HMS) and Warren Pear (U Penn)

Department of Pathology
Brigham and Women’s Hospital
Harvard Medical School
Harvard New Research Building
Room 652
77 Avenue Louis Pasteur
Boston, MA 02115

1.617.732.5500

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